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MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.. PLoS One. 13(1):e0190550.
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2017.
An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.. J Biol Chem. 292(37):15277-15286.
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2017. An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.. Cell. 169(2):350-360.e12.
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2017. Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.. Autophagy. 13(5):928-940.
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2017. A CRISPR Approach to Neurodegenerative Diseases.. Trends Mol Med. 23(6):483-485.
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2017. CRISPulator: a discrete simulation tool for pooled genetic screens.. BMC Bioinformatics. 18(1):347.
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2017. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.. J Biol Chem. 292(25):10328-10346.
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2017. Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells.. Chem Commun (Camb). 53(53):7162-7167.
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2017. Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury.. Cell Rep. 20(5):1136-1147.
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2017. Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.. Dev Cell. 43(6):744-762.e11.
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2017. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.. Sci Transl Med. 9(385)
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2017. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.. J Biol Chem. 292(47):19209-19225.
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2017. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.
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2017. A microRNA-mRNA expression network during oral siphon regeneration in .. Development. 144(10):1787-1797.
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2017. Molecular definitions of autophagy and related processes.. EMBO J. 36(13):1811-1836.
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2017. Multicellular hypothesis for the pathogenesis of Alzheimer's disease.. FASEB J. 31(5):1792-1795.
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2017. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.. Neuron. 95(3):531-549.e9.
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2017. Programmed mitophagy is essential for the glycolytic switch during cell differentiation.. EMBO J. 36(12):1688-1706.
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2017. Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others.. Neuron. 94(6):1112-1120.e4.
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2017. Store-Operated Ca Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism.. Cell Metab. 25(3):698-712.
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2017. Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.. Nat Commun. 8(1):300.
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2017. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.. Nat Med. 23(4):429-438.
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2017. Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.. Glia. 64(10):1788-94.
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2016. Design, Characterization, and Use of a Novel Amyloid β-Protein Control for Assembly, Neurotoxicity, and Gene Expression Studies.. Biochemistry. 55(36):5049-60.
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2016. New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo.. Neuron. 92(6):1181-1195.
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2016. Selective endosomal microautophagy is starvation-inducible in Drosophila.. Autophagy. 12(11):1984-1999.
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2016. Targeting microglia for the treatment of Alzheimer's Disease.. Glia. 64(10):1710-32.
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