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MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.. PLoS One. 13(1):e0190550.
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2018. Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease.. Neurobiol Aging. 52:71-80.
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2017. An acetylation-phosphorylation switch that regulates tau aggregation propensity and function.. J Biol Chem. 292(37):15277-15286.
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2017. An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.. Cell. 169(2):350-360.e12.
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2017. Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding.. J Neurosci Methods. 282:20-33.
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2017. Clinicopathological correlations in behavioural variant frontotemporal dementia.. Brain. 140(12):3329-3345.
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2017. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.. Mol Cell. 68(1):210-223.e6.
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2017. A CRISPR Approach to Neurodegenerative Diseases.. Trends Mol Med. 23(6):483-485.
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2017. CRISPulator: a discrete simulation tool for pooled genetic screens.. BMC Bioinformatics. 18(1):347.
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2017. Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem.. PLoS Med. 14(3):e1002260.
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2017. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes.. Neuropsychologia. 101:57-64.
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2017. Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells.. Chem Commun (Camb). 53(53):7162-7167.
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2017. Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways.. Dev Cell. 43(6):744-762.e11.
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2017. Frontotemporal Dementia.. Neurol Clin. 35(2):339-374.
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2017. Frontotemporal dementia with the V337M mutation: Tau-PET and pathology correlations.. Neurology. 88(8):758-766.
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2017. G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands.. Mol Pharmacol. 91(2):145-156.
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2017. Genome-wide association study identifies locus influencing human plasma tau levels.. Neurology. 88(7):669-676.
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2017. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.. Nat Genet. 49(2):193-203.
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2017. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.. Sci Transl Med. 9(385)
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2017. Inhibition of CRISPR-Cas9 with Bacteriophage Proteins.. Cell. 168(1-2):150-158.e10.
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2017. Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia.. Acta Neuropathol. 134(5):813-816.
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2017. Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery.. Alzheimers Dement. 13(3):236-246.
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2017. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.. Proc Natl Acad Sci U S A. 114(19):5029-5034.
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2017. A molecular signature for anastasis, recovery from the brink of apoptotic cell death.. J Cell Biol. 216(10):3355-3368.
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2017. Multicellular hypothesis for the pathogenesis of Alzheimer's disease.. FASEB J. 31(5):1792-1795.
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2017. Observing conversational laughter in frontotemporal dementia.. J Neurol Neurosurg Psychiatry. 88(5):418-424.
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2017. Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.. Neuron. 94(6):1101-1111.e7.
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2017. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.. Stem Cell Reports. 9(4):1221-1233.
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2017. Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.. Cell Rep. 21(2):517-532.
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2017. Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.. Acta Neuropathol. 133(5):825-837.
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2017. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency.. Cell Host Microbe. 21(5):569-579.e6.
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2017. Store-Operated Ca Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism.. Cell Metab. 25(3):698-712.
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2017. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.. Blood. 129(22):3000-3008.
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2017. Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.. Brain Imaging Behav. 11(2):391-400.
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2017. Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.. Nat Commun. 8(1):300.
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2017. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.. Nat Med. 23(4):429-438.
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2017. Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer's Disease.. J Alzheimers Dis. 58(4):1035-1041.
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2017. Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease.. FASEB J. 30(11):3853-3859.
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