2017
- A molecular signature for anastasis, recovery from the brink of apoptotic cell death. J. Cell Biol.. 216 (10): 3355-3368. PMID: 28768686. PMCID: PMC5626555.
- Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease. Neurobiol. Aging. 52 71-80. PMID: 28131013. PMCID: PMC5359035.
- Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy. Bioessays. 39 (4): PMID: 28083916. PMCID: PMC5903676.
- Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation. Sci Rep. 7 (1): 17377. PMID: 29234016. PMCID: PMC5727029.
- An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from gene mutations. Alzheimers Dement (N Y). 3 (4): 507-512. PMID: 29124108. PMCID: PMC5671622.
- An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells. Cell. 169 (2): 350-360.e12. PMID: 28388416. PMCID: PMC5616215.
- An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J. Biol. Chem.. 292 (47): 19209-19225. PMID: 28972160. PMCID: PMC5702663.
- Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding. J. Neurosci. Methods. 282 20-33. PMID: 28267565. PMCID: PMC5600818.
- Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation. Autophagy. 13 (5): 928-940. PMID: 28410006. PMCID: PMC5446085.
- Clinicopathological correlations in behavioural variant frontotemporal dementia. Brain. 140 (12): 3329-3345. PMID: 29053860. PMCID: PMC5841140.
- Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Mol. Cell. 68 (1): 210-223.e6. PMID: 28985505. PMCID: PMC5640507.
- CRISPulator: a discrete simulation tool for pooled genetic screens. BMC Bioinformatics. 18 (1): 347. PMID: 28732459. PMCID: PMC5521134.
- Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J. Biol. Chem.. 292 (25): 10328-10346. PMID: 28465352. PMCID: PMC5481548.
- Deconstructing empathy: Neuroanatomical dissociations between affect sharing and prosocial motivation using a patient lesion model. Neuropsychologia. PMID: 28209520. PMCID: PMC5773395.
- Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem. PLoS Med.. 14 (3): e1002260. PMID: 28323819. PMCID: PMC5360211.
- Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 101 57-64. PMID: 28427989. PMCID: PMC5765862.
- Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. Chem. Commun. (Camb.). 53 (53): 7162-7167. PMID: 28487920. PMCID: PMC5507204.
- Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury. Cell Rep. 20 (5): 1136-1147. PMID: 28768198. PMCID: PMC5565222.
- Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Dev. Cell. 43 (6): 744-762.e11. PMID: 29257953. PMCID: PMC5752135.
- Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study. PLoS Med.. 14 (3): e1002272. PMID: 28350795. PMCID: PMC5369701.
- Frontotemporal dementia with the V337M mutation: Tau-PET and pathology correlations. Neurology. 88 (8): 758-766. PMID: 28130473. PMCID: PMC5344079.
- Frontotemporal Dementia. Neurol Clin. 35 (2): 339-374. PMID: 28410663. PMCID: PMC5472209.
- G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands. Mol. Pharmacol.. 91 (2): 145-156. PMID: 27879340. PMCID: PMC5267521.
- Genome-wide association study identifies locus influencing human plasma tau levels. Neurology. 88 (7): 669-676. PMID: 28100725. PMCID: PMC5317386.
- Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 9 (385): PMID: 28404863. PMCID: PMC5526610.
- Inhibition of CRISPR-Cas9 with Bacteriophage Proteins. Cell. 168 (1-2): 150-158.e10. PMID: 28041849. PMCID: PMC5235966.
- Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia. Acta Neuropathol.. 134 (5): 813-816. PMID: 28828560. PMCID: PMC5645431.
- Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery. Alzheimers Dement. 13 (3): 236-246. PMID: 27513978. PMCID: PMC5298942.
- Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proc. Natl. Acad. Sci. U.S.A.. 114 (19): 5029-5034. PMID: 28438992. PMCID: PMC5441749.
- Mistakes, Too Few to Mention? Impaired Self-conscious Emotional Processing of Errors in the Behavioral Variant of Frontotemporal Dementia. Front Behav Neurosci. 11 189. PMID: 29089874. PMCID: PMC5651000.
- Molecular definitions of autophagy and related processes. EMBO J.. 36 (13): 1811-1836. PMID: 28596378. PMCID: PMC5494474.
- Multicellular hypothesis for the pathogenesis of Alzheimer's disease. FASEB J.. 31 (5): 1792-1795. PMID: 28100644.
- Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 95 (3): 531-549.e9. PMID: 28712653. PMCID: PMC5811312.
- Observing conversational laughter in frontotemporal dementia. J. Neurol. Neurosurg. Psychiatry. 88 (5): 418-424. PMID: 28235777. PMCID: PMC5726511.
- Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J.. 36 (12): 1688-1706. PMID: 28465321. PMCID: PMC5470043.
- Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron. 94 (6): 1101-1111.e7. PMID: 28641109. PMCID: PMC5568251.
- Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports. 9 (4): 1221-1233. PMID: 28966121. PMCID: PMC5639430.
- Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. Cell Rep. 21 (2): 517-532. PMID: 29020636. PMCID: PMC5637483.
- Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol.. 133 (5): 825-837. PMID: 28271184. PMCID: PMC5429027.
- SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 21 (5): 569-579.e6. PMID: 28494238. PMCID: PMC5490666.